Presentation Year

2022

Depreciated Participant

Joe Olage PasillasBiologyUndergraduate Student

College or Department

Short Description of your Research or Creative Project (700 characters or less)

Understanding the origins of hematopoietic stem cells has been a challenge due to the lack of a marker specific to this cell type. Recently, our lab has functionally proven that HoxB5 is a unique marker for long-term HSCs in adult murine models. Whether HoxB5 is also a marker for HSCs in development, has not been studied. Here, we are labeling HoxB5+ cells found in the yolk sac blood islands at E7.5 by using a genetic tool we generated. We will then analyze all marked cells at several time points during development and adulthood. This project will discover if HoxB5+ cells from the yolk sac contribute to the adult hematopoietic system and the LT-HSC pool.

Permission to Publish Work

Yes

Presentation File Upload

CIRM%20Poster%20Presentation.pptx.pdf (1.35 MB)

Node ID

1071

Page Classification